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Ellen Degeneres, Heches former partner, said in a statement on Twitter, This is a sad day.

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Im sending Annes children, family and friends all of my love.

Actress Rosanna Arquette simply wrote, Rest In Peace now Anne.

Read more tributes to the life and work of Anne Heche below.

This is a sad day.

I’m sending Anne’s children, family and friends all of my love.

Rest In Peace now Anne .

Six Days Seven Nights was one of the earliest romcoms I taped on VHS and watched over and over.

Also loved her Men in Trees ABC series.

I was in awe, and remember thinking, “This could really change things for people.”

Thank you for so bravely taking that step, Anne.

RIPpic.twitter.com/gmTxCPLlOx

Anne Heche news today is so heartbreaking.

A truly epic, vibrant spirit and a profound talent.Sending tremendous love and support to her family.

A post shared by Heather Duffy Boylston (@theheatherduffy)

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